The Diablo II Horadric Cube is a quest item obtained in Act II which can be used to complete several quests. In addition to that task, it can be also used as a permanent backpack to store additional items and create new ones. Items will be Identified by Cain while inside the Horadric Cube.
Transmuting Items
You can use the Horadric Cube's magical powers to Transmute items into a new item. Place the items into the Cube and hit the Transmute Button. Warning: Any additional items that are not a part of the formula will disappear with a successful Transmutation.
Transmuting Formulas
Listed below are recipes for the Diablo2 Horadric Cube. We will be revealing more recipes as they are discovered. Simply place the items in the first half of the equation into the DiabloII Horadric Cube and hit the Transmute Button to produce the item in the second half of the equation.
Diablo II  The Horadric Cube Recipes
Transmuting Formulae:
Place In Cube  Transmutes into  Notes  
3 Rings of any type  1 Random Amulet  Usually Produces Junk  
3 Amulets  1 Random Ring  Usually Produces Junk  
3 Health Potions + 3 Mana Potions  1 Rejuvenation Potion  Use this formula if you are in need of instant healing and/or mana. Any grade of Health/Mana Potion can be used.  
3 Health Potions + 3 Mana Potions + 1 Gem (Any Grade)  1 Full Rejuvenation Potion  Use this formula if you are in need of instant full healing and/or mana. Any grade of Health/Mana Potion or Gem can be used.  
3 Gems of the Same Type and Grade (lower than Perfect)  1 Higher Grade Gem of the Same Type  Use this formula to upgrade your growing masses of low quality Gems into something more useful.  
6 Gems (Any Grade) and 1 Sword  1 Socketed Long Sword  For those that are having trouble finding a socketed weapon. Any OneHanded Sword can be used.  
2 Quivers of Arrows  1 Quiver of Bolts  For users of Crossbows that are in need of ammunition. Random quantity of Bolts produced.  
2 Quivers of Bolts  1 Quiver of Arrows  For users of Bows that are in need of ammunition. Random quantity of Arrows produced.  
1 Spear + 1 Quiver of Arrows  1 Stack of Javelins  Mainly for Amazons that are in need of Javelins to use with skills. Any class/type of Spear can be used.  
1 Axe + 2 Daggers  Throwing Axe  Any class/type of Axe can be used (i.e. magic/socketed/non magical axe/etc). Random quantity of throwing axes produced.  
1 Ring + 1 Emerald + 4 Antidote Potions  1 Viridian Ring  Use this formula to create a Poison Resistance Ring. Any grade of Emerald can be used. The Viridian Ring has a random percentage of Poison Resistance  
1 Ring + 1 Ruby + 4 Exploding Potions  1 Garnet Ring  Use this formula to create a Fire Resistance Ring. Any grade of Ruby can be used. The Garnet Ring has a random percentage of Fire Resistance  
1 Ring + 1 Sapphire + 4 Thawing Potions  1 Cobalt Ring  Use this formula to create a Cold Resistance Ring. Any grade of Sapphire can be used. The Cobalt Ring has a random percentage of Cold Resistance  
1 Ring + 2 Topazes  1 Coral Ring  2130 Lightning resistance. Quality of gem and ring ingredients don't matter.  
3 Perfect Gems (of any type) + 1 Magic Item  1 New Random Magic Item of the Same Type  Use this formula to get specific statistics on a magic item, especially Exceptional Items.  
6 Perfect Gems (one of each type except skull) + Amulet  Prismatic Amulet  Use this formula to create an Amulet with Resistance to all.  
3 Perfect Skulls + 1 Amulet  High % chance of getting a +1 or +2 to char skills amulet  Any 3 perfect gems can be used, but skulls seem to have a higher success rate  
Wirt's Leg + Tome of Town Portal  Opens portal to the secret cow level  Must be done in the Rogue encampment after defeating Diablo on the same difficulty level you have defeated Diablo on.  
1 Diamond (any quality) + 1 Staff (any type and quality) + 1 Kris (any type and quality) + 1 Belt (any type and quality)  Savage Bardiche  
1 Small Shield (magical or better) + 1 Spiked Club (any quality) + 2 Skulls (any quality)  Small Shield of Spikes  
Strangling Gas Potion + any type of Healing Potion  1 Antidote Potion  
3 Perfect Gems (of any type) + 1 Magic Item  1 New Random Magic Item of the Same Type  You can use this formula to get another chance at a Magic Item of the same type. The ilvl=100. This means that any Magical Prefix or Suffix with a level of 100 or less (which is all of them) is available. You can use this formula (with an Amulet) to create a +2 Skills Amulet. This is helpful because the only monster that could drop one is Diablo on Hell Difficulty (since he's Level 90,). And you cannot Gamble one before Character Level 84. Be warned however, that the chances of getting that on an Amulet might be very low (considering everything is available) and it might take a lot of tries. Rare Items cannot be used with this formula to create new Rare Items.  
4 Health Potions (of any type) + Ruby (any type) + Magical/Set/Rare Sword (Any type)  Long Sword of the Leech  You can use this formula to get a Life Stealing Long Sword.  
6 Perfect Skulls + 1 Rare Item  1 Random Rare Item of the Same Type  You can use this formula to get another chance at a Rare Item of the same type. ilvl=100. Be warned that if you use a Sword you may get a Socketed Longsword instead. This formula will not work on items larger than 3x2. 

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